Comparative Histology

1 NSH Contact Hour(s)

(based on 1 customer ratings)

NSH members save $5. If you're a member of NSH, enter your e-mail here to get the member price »

Richard A. Peterson II, DVM, PhD, Diplomate ACVP; GlaxoSmithKline, Safety Assessment, RTP, USA

The use and translation of animal models of human disease requires a strong understanding of the anatomy, physiology and pathobiology of each specific model. This presentation will provide an overview highlighting key species differences in the liver, gastrointestinal tract, kidney, reproductive tract, central nervous system, and skin of commonly utilized laboratory animal models including: rodents, genetically-engineered mice, beagle dogs, non-human primates, and the mini-pig; using an organ system approach. A step-wise correlation of gross anatomic, light microscopic (H&E), and ultrastructural morphology will give the attendees an appreciation of the biological complexity as species-related systemic differences are characterized. The presentation will conclude with a discussion on commonly encountered spontaneous “background” lesions in key laboratory animal species (e.g., chronic progressive nephropathy in rodents) as well as several examples of unusual test article-related lesions encountered in non-clinical drug development. The session will provide a solid overview that will allow the attendees to confidently work with these animal models.

See more courses in: General Histology; Veterinary/Research

Included In These Course Packages

Continuing Education Credits

NSH Contact Hours (acceptable for AMT, ASCP, and state recertification): 1 hour(s)
Course number VIR111315

Customer Ratings

(based on 1 customer ratings)

Additional Information

Course Description: The use and translation of animal models of human disease requires a strong understanding of the anatomy, physiology and pathobiology of each specific model. This presentation will provide an overview highlighting key species differences in the liver, gastrointestinal tract, kidney, reproductive tract, central nervous system, and skin of commonly utilized laboratory animal models including: rodents, genetically-engineered mice, beagle dogs, non-human primates, and the mini-pig; using an organ system approach. A step-wise correlation of gross anatomic, light microscopic (H&E), and ultrastructural morphology will give the attendees an appreciation of the biological complexity as species-related systemic differences are characterized. The presentation will conclude with a discussion on commonly encountered spontaneous “background” lesions in key laboratory animal species (e.g., chronic progressive nephropathy in rodents) as well as several examples of unusual test article-related lesions encountered in non-clinical drug development. The session will provide a solid overview that will allow the attendees to confidently work with these animal models.

Additional Information: This webinar was presented in November 2015 as part of the NSH Veterinary & Research Scientist Webinar Series.

How to Subscribe
Veterinary and Research Scientist Webinar Series
Package of 5 online courses$120
NSH members save $20
Add to cart
Single online course$30
NSH members save $5
Add to cart
  • Order for instant access through any computer, any browser.
  • No shipping, faxing, or waiting for certificates.
  • Print or save your certificate of completion as soon as you've completed the course.
  • You'll have a full year (365 days) to complete your purchased courses.
Comparative Histology Image on OLC



 
Learn.NSH.org's design and platform are provided by MediaLab, Inc.